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Acanthosis Nigricans

Overview

A skin condition characterized by increased pigmentation (darkening of the skin) and hyperkeratosis (thickening of the skin). It occurs most commonly in the flexural skin areas (behind knee, front of elbow, neck, etc.). The disorder is related to insulinmetabolism and appears in diseases which affect insulin metabolism including obesity . In adults the condition may be associated with malignant tumors.


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Causes

This can affect person of any age, however it is common in adults and people with dark colored skin. Both males and females are equally affected

People who are at higher risk include:

  • Obese or overweight people
  • Any endocrine abnormality
  • Person on certain medicines like corticosteroids and oral contraceptive
  • Any internal malignancy
  • Kidney disease

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Signs & Symptoms

Acanthosis nigricans does not cause any symptoms apart from discoloration of skin. Eventually skin becomes thick, velvety appearance with marks and creases

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Prevention

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Treatments
Conservative Treatment Modern Medicine

Acnthosis only causes change in appearance of skin, so no particular treatment is required. However it is important to screen and treat the underlying cause.

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